amitiza/edema

I have been on amitiza and have had terrible swelling...about 8 lbs of water weight. My belly, legs and ankles all have 3 pit edema. I also get veery nausiated. It's been very difficult.<br>Has anyone else had this?

I have also noticed swelling in my hands and feet. I'm only taking one per day and I have the swelling and weight gain, but no help with my constipation! I thought I was imagining things. Now I know I'm not alone.

[ccfbarb]

I have been on Amitiza for about 3 months and thought I had a wonder drug as I suffer from chronic constipation. I had watery stools, but it was way better than not going. Now, it seems that my body had gotten used to the drug and is not responding like it did before. I now am noticing nausea, extreme bloating in my abdomen, wt. gain, and difficulty breathing. I'm considering stopping this drug to see if things improve.
Barb

[cjstudent]

Yeah, me too. I'm taking several meds like for blood pressure and cholesterol, but I had to look up which drug is making me gain this water weight? Sure enough, it's the Amitiza. I'll just go back to the Colace and herbal laxatives. Thanks for posting this! It helped me understand.
Dave